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J Intern Med ; 292(4): 679-683, 2022 10.
Article in English | MEDLINE | ID: covidwho-1916204

ABSTRACT

There are increasing reports of immune-mediated and para-infectious syndromes beyond the well-known respiratory manifestations of severe-acute-respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, the spectrum of severe neurological sequelae of SARS-CoV-2 remains undefined. We present the case of a 66-year-old female with rapidly progressive lower limb neurology 3 days post SARS-CoV-2 infection. Clinical and radiological findings were in keeping with transverse myelitis and treatment success was achieved with methylprednisolone and remdesivir. This report will discuss the associations between SARS-CoV-2 and acute transverse myelitis. We believe this is one of few described cases of early SARS-CoV-2-associated transverse myelitis secondary to neurotropism and the first successfully treated with the inclusion of remdesivir in the therapeutic regimen.


Subject(s)
COVID-19 , Myelitis, Transverse , Aged , COVID-19/complications , Female , Humans , Methylprednisolone/therapeutic use , Myelitis, Transverse/drug therapy , Myelitis, Transverse/etiology , SARS-CoV-2
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